Before the system theory came into being, our
understanding of biology is still based on the basis of decomposition and
reduction. If we're stuck in reductionism, many complex autoimmune diseases,
such as Rheumatoid arthritis (RA), will be difficult to understand. With the
emergence of complex networks in 1989, understanding of biological networks has
been enhanced. In this book the author presents the management strategy of RA from the
perspective of complex network.
RA is the most common chronic autoimmune joint disease.
This book argues that the RA is mainly caused by chronic stress and
stress factors include physical and psychological stress. Existing statistical
techniques based on reductionism cannot discover many relevant disease risk
factors and complex interaction relationship. The disease network model based
on complex network is important for the analysis and treatment of RA disease.
In this book, the author have found five important layers
of RA complex network and presented five balances regulating strategy in the
management of RA. Using this method, the author takes a two-year follow-up to check
the effect.
This Book argues RA is selflimiting to some extent, and
good management with five balances regulating strategy would have positive
significance, among which the balance between neuroendocrine system and immune
system is the most important. All five balances
regulating strategy are important for RA with other causes besides the RA case
in the book.