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https://doi.org/10.1148/rg.274065142

has been cited by the following article:

• TITLE: “FISH VERTEBRA” about 3 Sickle Cell Patients Followed at Laquintinie Hospital, Douala

  AUTHORS: Same Bebey Francine, Mbono Betoko Ritha, Eloundou Onomo Paul, Mantho Fopa Pauline, Eposse Ekoube Charlotte, Megne Tamo Estelle, Ebene Mbende Romain, Singwe Ngandeu Madeleine

  KEYWORDS: Vertebral Fractures, Sickle Cell Anemia, Vertebral Bone Fragility

  JOURNAL NAME: Open Journal of Rheumatology and Autoimmune Diseases, Vol.14 No.1, February 19, 2024

  ABSTRACT: Vertebral involvement in particular is common in sickle cell patients. We report 3 cases of “fish vertebra” fractures in sickle cell patients aged 16, 18, and 24 years old respectively at Laquintinie Hospital, Douala. When the vertebral fractures were diagnosed, the 3 patients had back pain and kyphosis deformities of the dorsal spine. Treatment with an infusion of biphosphonates (zoledronic acid at a dose of 0.5 mg·per·kg) was offered to all three patients. Two out of three patients received treatment with biphosphonates with a successful outcome. Profound vitamin D deficiency is associated with increased bone remodeling and a history of fractures. In sickle cell anemia, vertebral fractures may also result from bone fragility, which is often overlooked as aseptic osteonecrosis and osteomyelitis, which are very often suspected.