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has been cited by the following article:

• TITLE: Khat Chewing Induce Transient Elevation of Blood Pressure: By Using 24-Hour Ambulatory Blood Pressure Monitoring, in Yemen Republic

  AUTHORS: Dhaifullah Jayed, Mohamed Ali Al-Huthi, Aziz Al-Zandani, Salah Al-Shuki, Mohamed Al-Dholae, Mohamed Kasem Salah

  KEYWORDS: Khat Chewing, Systolic Blood Pressure, Diastolic Blood Pressure, Ambulatory Blood Pressure Monitoring, Yemen

  JOURNAL NAME: Open Access Library Journal, Vol.10 No.6, June 20, 2023

  ABSTRACT: Background: Khat or Catha edulis is an indigenous plant in Yemen, Ethiopia and East Africa, which has sympathomimetic and euphoriant effects. It is chewed habitually by people for its pleasurable effect and it produces stimulant amphetamine-like effects. Aims: The main aim is to study the effects of khat chewing on blood pressure and heart rate by using ambulatory blood pressure monitoring (ABPM). Methods: This was a cross-sectional, observational study in a group of 255 individuals aged 18 - 70 who visited our cardiac center from May 1, 2021, to January 1, 2023, chewing or non-chewing khat, All individuals underwent 24 hours of ambulatory blood pressure monitoring. Result: 255 adults are included, 70.6% of whom were khat chewers and 29.4% of whom were non-chewers. The two groups were comparable in most characteristics, and there were no significant differences between the two groups in terms of age, sex, and body mass index but they were significantly different in smoking. Only automatic BP measurements of 4 hours during khat chewing and 4 hours post-khat chewing show significant differences between khat chewers and non-chewers on both systolic (146.2 ± 8.1) versus (128.9 ± 12.1) P Conclusion: Khat chewing is associated with a transient increase in systolic and diastolic blood pressure and a transient increase in heart rate as well. Other clinical factors, such as BMI and smoking were significantly associated with hypertension.