TITLE:
Neutrophil to Lymphocyte Ratio in Acute Ischemic Stroke
AUTHORS:
Menat-Allah Mohamed Lashin, Salma Hamed Khalil, Taha Kamel Alloush, Sherif Anis, Mohamed Mahmoud Fouad
KEYWORDS:
Neutrophil to Lymphocyte Ratio, Acute Ischemic Stroke
JOURNAL NAME:
Neuroscience and Medicine,
Vol.11 No.2,
June
4,
2020
ABSTRACT: Introduction: The neutrophil to lymphocyte ratio (NLR) can be used as a marker of subclinical inflammation, and may have a predictive power in prognosis and severity of atherosclerosis-related diseases. This study aimed to assess an association between the NLR, and clinical characteristics and one-month outcome in acute ischemic stroke (AIS). Subjects and Methods: This case-control observational prospective study included 75 patients admitted to stroke unit of Ain Shams University hospitals with AIS, sub grouped into 3 equal groups according to subtype of AIS, in addition to 25 healthy individuals. The demographic characteristics of the patients, complete blood picture test results at presentation, National Institutes of Health Stroke Scale (NIHSS) scores and modified Rankin Scale (mRS) scores were recorded. The clinical outcome was assessed by the NIHSS and mRS scores after one month. Results: The total leucocyte count was significantly higher in large artery atherosclerosis (P = 0.004) and cardioembolic (P = 0.020) stroke groups, unlike lacunar stroke group (P = 0.082), when compared to controls. The neutrophils count was higher (P Conclusion: NLR was significantly higher among AIS subtypes compared to controls, but not a good predictor for one month outcome.