TITLE:
Anti-Hemorrhoidal Medicinal Plants of the Department of Issia: Inventory and Cytotoxicity on HFF Cells of the Ethanolic Extract 70% of Landolphia utilis A. Chev. (Apocynaceae)
AUTHORS:
Coulibaly Kiyinlma, Etien Dibié Théodore, Orso Bosson Arobia Marie Bernadine, Kanga Yao, Zirihi Guédé Noël
KEYWORDS:
Hemorrhoids, ICF, Medicinal Plants, Tradipractitioners
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.7 No.11,
November
11,
2019
ABSTRACT: Objective: To
identify the anti-hemorrhoidal medicinal plants of the Department of Issia and evaluate the cytotoxic activity of
the most requested species. Methods: The
plants used in hemorrhoid recipes in the Department of Issia (Côte d’Ivoire)
were obtained using a semi-structured survey based on a questionnaire sheet. To
assess the use of plants on the disease, Informant Consensus Factors (ICF) for
each species were calculated. The harvested species were identified at the
Centre National de Floristique (CNF) of the Félix Houphouët Boigny University
(Côte d’Ivoire). Cytotoxicity tests were performed
on HFF cells with the 70% ethanolic extract, prepared from the aqueous
extract of the most cited species. Results: A total of twenty four
medicinal species in eighteen families were recorded. Among these taxa are ten
woody and fourteen herbaceous. Only three species gave an ICF greater than 0.5.
The ethanolic extract 70% of the frequently requested medicinal plant did not
reveal any toxicity on HFF cells. Conclusion: These results revealed
that the flora of the Department of Issia is rich in anti-hemorrhoidal
medicinal plant species. Their use without side effects is revealed by the
absence of toxicity in one of the most solicited plants.