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Tagat, J.R., Steensma, R.W., McCombie, S.W., Nazareno, D.V., Lin, S.I., Neustadt, B.R., et al. (2001) Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-(2,4-dimethyl-3-pyridinyl)carbonyl-4-methyl-4-3(S)-methyl-4-1(S)-4-(trifluoro-methyl)phenylethyl-1-piperazinyl-piperidine N1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist. Journal of Medicinal Chemistry, 44, 3343-3346.
https://doi.org/10.1021/jm0155401
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