Dr. Rita Kumar

Department of Emergency Medicine and Physiology

Wayne State University, USA

Assistant Professor

Email: rkuma@med.wayne.edu

Qualifications

2001 Ph.D., Wayne State University, USA, Physiology

1998 M.Sc., Wayne State University, USA, Biology

1995 B.Sc., University of Windsor, Canada, Biology

Publications

1. Sanderson TH, Raghunayakula S, Kumar R. Neuronal hypoxia disrupts mitochondrial fusion. Neuroscience. 2015 Jun 3. pii: S0306-4522(15)00529-1.
2. Sanderson TH, Gallaway M, Kumar R. Unfolding the Unfolded Protein Response: Unique Insights into Brain Ischemia. Int J Mol Sci. 2015; 16(4):7133-7142.
3. Sanderson TH, Raghunayakula S, Kumar R. Release of Mitochondrial Opa1 following Oxidative Stress in HT22 cells. Molecular and Cellular Neuroscience. 2015; 64: 116-122.
4. Sanderson TH, Mahapatra G, Pecina P, Ji Q, Yu K, Sinkler C, Varughese A, Kumar R, Bukowski MJ, Tousignant RN, Salomon AR, Lee I, Hüttemann M. Cytochrome c is tyrosine 97 phosphorylated by neuroprotective insulin treatment. PLoS one. 2013; 8(11):e78627.
5. Calo L, Dong Y, Kumar R, Przyklenk K, Sanderson TH. Mitochondrial Dynamics: an Emerging Paradigm in Ischemia-Reperfusion Injury. Current Pharmaceutical Design. 2013; 19: 6848-57.
6. Sanderson TH, Reynolds CA, Kumar R, Przyklenk K, Hüttemann M. Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal role of the mitochondrial membrane potential in reactive oxygen species generation. Mol Neurobiol. 2013; 47(1): 9-23.
7. Lagina A, Calo L, Deogracias M, Sanderson TH, Kumar R, Sullivan JM. Combination Therapy with IGF-1 and Hypothermia Synergistically Improves Outcome After Transient Cerebral Ischemia in the Rat. Academic Emergency Medicine. 2013; 20(4): 344-51.
8. Sanderson TH, Deogracias MP, Nangia KK, Wang J, Kumar R. PKR-like endoplasmic reticulum kinase (PERK) activation following brain ischemia is independent of unfolded nascent proteins. Neuroscience. 2010; 169(3): 1307-14.
9. Sanderson TH, Kumar R, Murariu-Dobrin AC, Page AB, Krause GS, Sullivan M. Insulin induces phosphatidylinositol-3 kinase-dependent phosphorylation of Akt in vulnerable neurons after transient global brain ischemia. Neurol Res. 2009; 31(9): 947-58.
10. Miller CD, Kumar R, Storrow AB. Alignment of emergency medicine research efforts with Clinical and Translational Science Awards. Acad Emerg Med. 2008; 15(7): 672-7.
11. Sanderson TH, Kumar R, Sullivan JM, Krause GS. Insulin blocks cytochrome c release in the reperfused brain through PI3-K signaling and by promoting Bax/Bcl-XL binding. J Neurochem 2008; 106(3): 1248-58.
12. Miller JM, Kumar R, McAllister II JP, Krause GS. Gene Expression Analysis of the Development of Congenital Hydrocephalus in the H-Tx Rat. Brain Res 2006; 1075(1): 36-47.
13. Owen CR*, Kumar R*, Zhang P, McGrath BC, Cavener DR, Krause GS. Perk is necessary and sufficient for the large increase in eIF2α (P) phosphorylation immediately after transient brain ischemia. J Neurochem. 2005; 94: 1235-1242. (*1st and 2nd authors contributed equally).