TITLE:
Investigating Catalase and Carbonic Anhydrase Enzyme Activities and Levels of Certain Trace Elements and Heavy Metals in Patients with Primary and Metastatic Hepatic Carcinoma
AUTHORS:
Ayse Arslan, Halit Demir, Harun Arslan
KEYWORDS:
Primary and Metastatic Liver Cancer; Catalase; Carbonic Anhydrase; Trace Element; Heavy Metal
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.4 No.8,
October
29,
2013
ABSTRACT:
Hepatocellular carcinoma (HCC) is among most common
terminal cancer types in the world. Primary etiological factors include
cirrhosis, hepatitis, aflatoxin and alcohol. The current study was conducted to
determine cytosolic erythrocyte carbonic anhydrase and catalase enzyme
activities and levels of some trace elements. For this purpose, 40 patients
with primary and metastatic hepatic cancer and 29 healthy volunteers enrolled
to the study. Catalase and carbonic anhydrase enzyme activities and serum trace
element levels were measured in patient and control groups. In the current
study, serum copper, magnesium, manganese and zinc levels were lower in the
primary and metastatic hepatic cancer group in comparison with the control
group (P