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has been cited by the following article:

• TITLE: The Fusability of Erythrocytes as a Method for Evaluating the Instability of Their Membranes

  AUTHORS: Yury A. Sheremet’ev, Aleksandra N. Popovicheva, Methun M. Rogozin, Gregory Y. Levin

  KEYWORDS: Erythrocytes; Fusability; Membrane Instability; La3+

  JOURNAL NAME: Open Journal of Biophysics, Vol.3 No.3, July 12, 2013

  ABSTRACT: A novel approach to the study of erythrocytes instability based on assessment fusability of their plasma membrane is presented. The fusability of erythrocytes normal blood, stored for 7 days at 4°C, and type 2 patients with diabetes were studied. Human erythrocytes were fused by incubation with La3+ at final concentrations from 50 to 200 μM. Erythrocytes aggregates were incubated at 37°C for 120 min. The fusability of erythrocytes was evaluated using a light microscope. It was shown that La3+ induced extensive fusion of erythrocytes after 7 days of blood storage and erythrocytes of patients with diabetes. Incubation of normal erythrocytes at 37°C for 120 min does not induce cell fusion.