L. Xiao, T. B. Ng, Y. B. Feng, T. Yao, J. H. Wong, R. M. Yao, L. Li, F. Z. Mo, Y. Xiao, P. C. Shaw, Z. M. Li, S. C. W. Sze and K. Y. Zhang, “Dendrobium candidum Extract Increases the Expression of Aquaporin-5 in Labial Glands from Patients with Sj?gren’s Syndrome,” Phytomedicine, Vol. 18, No. 2-3, 2011, pp. 194-198.

has been cited by the following article:

• TITLE: Immunopotentiating Activity of Dendrobium Species in Mouse Splenocytes

  AUTHORS: David T. W. Lau, Michel K. T. Poon, Hoi Yan Leung, Kam Ming Ko

  KEYWORDS: Dendrobium Offincalis, Dendrobii Caulis, Splenocyte Proliferation, Concanavalin A

  JOURNAL NAME: Chinese Medicine, Vol.2 No.3, September 30, 2011

  ABSTRACT: This study aimed to explore a pharmacological activity marker for quality assurance of Dendrobium species. The immunopotentiating activity in aqueous extracts prepared from four Dendrobium species, including D. officinalis, was assessed by an in vitro assay of concanavalin A (Con A)-stimulated proliferation of mouse splenocytes. Four samples of commercially available Dendrobii Caulis were also analyzed for comparison. The results indicated that the aqueous extract of D. officinalis produced immunopotentiating action, as evidenced by the increase in Con A-stimulated proliferation of mouse splenocytes, with the extent of stimulation being more prominent than those of other tested Dendrobium species and Dendrobii Caulis samples. In conclusion, an in vitro immunopotentiation assay may be used for assessing the pharmacological activity of Dendrobium species. The finding that D. officinalis produced a more potent immunopotentiating action is consistent with its yin-nourishing action in Chinese medicine, which is more effective than other Dendrobium species in clinical use.