TITLE:
Malignant Transformation of Cerebellar Pleomorphic Xanthoastrocytoma: A Case Report
AUTHORS:
Oumar Coulibaly, Mahamadou Dama, Oumar Diallo, Quenum Kouassi Jean Marie Maurin Kisito, Li Gu, Boubacar Sogoba, Moussa Denou, Sieleche Auxence Christ, Youssouf Sogoba, Mamadou Salia Diarra, Alpha Singuépiré, Drissa Kanikomo
KEYWORDS:
Pleomorphic Xanthoastrocytoma, Cerebellar, Malignant
JOURNAL NAME:
World Journal of Neuroscience,
Vol.7 No.4,
October
30,
2017
ABSTRACT: Pleomorphic xanthoastrocytoma
(PXA) generally occurs in children and young adults and is
classified as a low-grade astrocytic tumor with a potential favorable
prognosis. But these data must be interpreted with much caution, because of
some rapid progression or malignant transformation during the postoperative
follow-up. We report herein a rare case of a cerebellar PXA manifested as a benign lesion at first time in a 39 year-old
woman, but with malignant transformation two years later. In this paper,
we discuss the clinical signs, radiological findings and the therapeutic data
on the subject according to literature review.