TITLE:
Use of Oral Agents and/or Insulin in the Treatment of Diabetes during Pregnancy: An Examination of Outcomes in Pregestational versus Gestational Diabetics
AUTHORS:
Edwin Henslee, Amanda Hatton, Selman I. Welt, Jennifer Holmes, Lindsay Penrose, Samuel Prien, Naghma Farooqi
KEYWORDS:
Diabetes, Pregnancy, Treatment Methods, Pump, Oral Agents
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.4 No.16,
December
8,
2014
ABSTRACT: The management of diabetes
in pregnancy varies depending on whether the condition was first diagnosed
during pregnancy (gestational diabetes) or was diagnosed before pregnancy
(pregestational diabetes). Little has been published comparing the relative
efficacy of various oral agents for the treatment of gestational diabetes and
the reported experience with the insulin pump in pregnancy for pregestational
diabetes remains meager. We conducted a retrospective chart review of women
managed in a specialized diabetic clinic to compare the results of treatment of
gestational diabetes with oral agents, glyburide and acarbose, to those treated
with split-mixed insulin and treatment of pregestational diabetes with either
the insulin pump or conventional splitmixed insulin. Gestational diabetics
treated with split-mixed insulin were hospitalized significantly more often (p