TITLE:
Exploring diversity of different classificatory human tandem repeats
AUTHORS:
Zhong-Yu Liu, Xu-Feng Li, Xian-Ping Ding, Bo Liu, Yi Yang
KEYWORDS:
Diversity of different classificatory, Human tandem repeats
JOURNAL NAME:
Journal of Biomedical Science and Engineering,
Vol.1 No.2,
August
25,
2008
ABSTRACT: Tandem repeats (TRs) are associated with dis-ease genes, play an important role in evolution and are important in genomic organization and function. Much research has been done on de-scriptions of properties of tandem repeats, such as copy-number, period, etc, and correlation be-tween mutations within tandem repeats and dis-ease. This project aims to detect some differ-ences which may exist within the features of dif-ferent tandem repeats associated with disease in human whole-genome. The features of tandem repeats associated with diabetes genes were compared to the counterparts of non-diabetes disease genes.