Isolated Multifocal Sclerosing Thyroiditis: Case Report

Annalisa Paliotta, Giuseppe Pedullà, Daniele Crocetti, Giuseppe Cavallaro, Giuseppe D’Ermo, Andrea Polistena, Giorgio De Toma

Department of Surgery “Pietro Valdoni”, Policlinico Umberto I, University of Rome “Sapienza”, Rome, Italy.

DOI: 10.4236/ss.2013.43040                

Abstract

Multifocal fibrosclerosis is a very rare fibroproliferative syndrome involving multiple organ systems. In our report we present the case of multifocal sclerosing thyroiditis characterized by multiple fibroelastic foci similar to breast “radial scar”, which can be misdiagnosed as multifocal papillary carcinoma. The diagnosis of multifocal sclerosing thyroiditis, in according with Armed Forces Institute of Pathology (AFIP) textbook on thyroid tumors, was made only after histological and himmunohistochemical examination. We consider the multifocal sclerosing thyroiditis as the first stage of multifocal IgG4-related sclerosing disease for the presence of IgG4 within fibrosclerotic tissue of thyroid. Total body CT-scan and plamatic IgG4 levels must be investigated in order to exclude or confirm the presence of systemic disease.

Keywords

Multifocal Sclerosing Thyroiditis; Surgery; IgG4-Related Sclerosing

Conflicts of Interest

The authors declare no conflicts of interest.

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