Dr. Zhen Zhang

Genentech, Inc., USA

Email:zhangz28@gene.com

Qulification

1999-2002 M.Sc., Institute of Genetics, Fudan University, China

1995-1999 B.Sc., School of Life Sciences, Fudan University, China

Publications

1. Zhang, Z., O'Rourke, J.R., McManus, M.T., Lewandoski, M., Harfe, B.D., and Sun, X. (2011).The microRNA-processing enzyme Dicer isdispensable for somite segmentation but essential for limb bud positioning.Dev Biol 351, 254-265.
2. Zhang, Z., Sui, P., Dong, A., Hassell, J., Cserjesi, P., Chen, Y.T., Behringer, R.R., and Sun, X. (2010). Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.Development 137, 3417-3426.
3. Zhang, Z., Verheyden, J.M., Hassell, J.A., and Sun, X. (2009). FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds. Dev Cell 16, 607-613.
4. Norman, R.X., Ko, H.W., Huang, V., Eun, C.M., Abler, L.L., Zhang, Z., Sun, X., and Eggenschwiler, J.T. (2009).Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.Hum Mol Genet 18, 1740-1754.
5. Harris, K.S., Zhang, Z., McManus, M.T., Harfe, B.D., and Sun, X. (2006). Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A 103, 2208-2213.
6. Wang, S., Zhang, Z., Ying, K., Chen, J.Z., Meng, X.F., Yang, Q.S., Xie, Y., and Mao, Y.M. (2003). Cloning, expression, and genomic structure of a novel human Rap2 interacting gene (RPIP9).Biochem Genet 41, 13-25.
7. Wang, S., Chen, J.Z., Zhang, Z., Gu, S., Ji, C., Tang, R., Ying, K., Xie, Y., and Mao, Y. (2003). Cloning, expression and genomic structure of a novel human GNB2L1 gene, which encodes a receptor of activated protein kinase C (RACK). Mol Biol Rep 30, 53-60.
8. Zhang, Z., Wu, C., Huang, W., Wang, S., Zhao, E., Huang, Q., Xie, Y., and Mao, Y. (2002a). A novel human gene whose product shares homology with bovine brain-specific protein p25 is expressed in fetal brain but not in adult brain. J Hum Genet 47, 266-268.
9. Zhang, Z., Wu, C., Wang, S., Huang, W., Zhou, Z., Ying, K., Xie, Y., and Mao, Y. (2002b).Cloning and characterization of ARHGAP12, a novel human rhoGAP gene. Int J Biochem Cell Biol 34, 325-331.
10. Wang, S., Chen, J.Z., Zhang, Z., Huang, Q., Gu, S., Ying, K., Xie, Y., and Mao, Y. (2002).Cloning, characterization, and expression of calcyphosine 2, a novel human gene encoding an EF-hand Ca(2+)-binding protein. Biochem Biophys Res Commun 291, 414-420.