Prof. Andrei P. Surguchov
Kansas University Medical Center, USA
Email: asurguchov@kumc.edu
Qualifications
Ph.D., Molecular Biology, Cardiology Research Center, Russia
M.Sc., Molecular Biology, Moscow State University, Russia
B.Sc., Biochemistry, Moscow State University, Russia
Publications (selected)
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A.P. Surguchov, M.V. Telkov and V.N. Smirnov. 1986. Absence of structural homology between sup1 and sup2 genes of yeast S. cerevisiae and identification of their transcripts. FEBS Letters, 206,1, 147 - 150
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Kushnirov, V.V., Ter-Avanesyan, M.D., Surguchov, A.P., Smirnov, V.N., Inge-Vechtomov, S.G. 1987. Localization of possible functional domains in sup2 gene product of the yeast S. cerevisiae. FEBS Letters, 215, 2, pp.257 - 260
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Kushnirov V.V., Ter-Avanesyan, M.D.,Surguchov A.P., V.N. Smirnov, S.G. Inge-Vechtomov. 1988. Nucleotide sequence of the sup2 gene of yeast S. cerevisiae. Gene, 66, pp. 45 - 54
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V.A. Kosykh, A.P. Surguchov, E.E. Podrez, V.N. Smirnov. 1988. 7-ketocholesterol inhibits VLDL secretion by cultured human and rabbit hepatocytes. Biochim Biophys Res Comm 153, 3, pp. 1116 - 1122
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V.A. Kosykh, E.A. Podrez, A.B. Novikov, A.P.Surguchov, V.N. Smirnov.1988. VLDL apoprotein secretion and apoB mRNA level in primary cultures of cholesterol loaded rabbit hepatocytes. FEBS Letters, v. 232, 1, pp. 103 - 106
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A.P. Surguchov. 1987. Common genes for mitochondrial and cytoplasmic proteins. Trends in Biochemical Sciences (TIBS). v. 12, 9, pp. 335 - 339
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A.P. Surguchov. 1988. Omnipotent nonsense suppressors : new clues to an old puzzle. Trends in Biochemical Sciences (TIBS), v. 13, 4, pp. 120 - 123
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A.B. Sudarikov and A.P. Surguchov. 1988. Probe for rabbit apolipoprotein B gene. Nucleic Acids Research, v.16, 16, p. 8187
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A.P. Surguchov. 1990. Apolipoprotein gene family : organization of upstream elements and regulation of gene expression. Biomedical Sciences, Turpin Transactions Ltd., Pion Ltd., v. 1, No. 4, pp. 344 - 354
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A.P. Surguchov . 1991. Migration of promoter elements between genes : a role in transcriptional regulation and evolution. Biomedical Sciences (Turpin Transactions Ltd., Pion Ltd.) , v. 2, pp. 22 - 28
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A.P. Surguchov, E. Boerwinkle, R. Sharett, W. Patsch. 1994. Apolipoprotein E genotype and plasma lipid transport : insight into the role of the E4 allele from populational studies. Atherosclerosis, v.106, p.119
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A.P. Surguchov, S. Liu, W. Patsch. 1995. Simple non-radioactive methods of analysis of polymorphic markers flanking human apolipoprotein C-III gene. Disease Markers, v. 12, pp. 167 - 174
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Y.Ch. Lin-Lee, S. Soyal, S. Sanders, A. Surguchov, W. Patsch, 1995 Thyroid hormone influences conditional transcript elongation of the apolipoprotein A-I gene in rat liver. J. Lipid Research , v. 36, pp. 1586-1595.
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A.P. Surguchov, G.P. Page, L. Smith, W. Patsch, E. Boerwinkle. 1996. Polymorphic markers in apo-lipoprotein C-III gene flanking regions and hyper- lipoproteinemia. Arteriosclerosis, Thrombosis and Vascular Biology, v.16, 8, pp.941-948
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I.G. Surgucheva, W. Baehr, A. Surguchov. 1997. Differential effect of expression of heterologous genes in baculovirus transfer vector on the level of baculovirus protein expression. Mol Biol of the Cell, 139, 806
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Surguchov, I.Surgucheva, K. Howes, W. Baehr. 1999. Synoretin - a new retina protein belonging to the synuclein family. Mol Cell Neurosci, 13, 95-103.
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Surguchov, B. McMahon, E. Masliah, I. Surgucheva. 2001. Synucleins in ocular tissues. J Neurosci Res, 65, 68-77
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A Surguchov, RE. Palazzo, and I Surgucheva. 2001. Gamma synucleins: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction. Cell Motility and Cytoskeleton, 2001, 49, 218-228
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Pronin AN, Morris AJ, Surguchov A, Benovic JL. 2000. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem., 275, 26515-26522
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Surgucheva I., McMahan B, F. Ahmed , Tomarev S, Wax MB, Surguchov A. 2002. Synucleins in glaucoma: implication of gamma-synuclein in glaucomatous alterations in the optic nerve. J Neurosci Res, 68: 97-106.
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Surgucheva I, Sivak, JM, Fini ME, Palazzo RE and Surguchov AP. 2003. Effect of gamma-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells. Arch Biochem Biophys. 410:167-176.
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Maurage CA, Ruchoux MM, De Vos R, Surguchov A, Destee A. 2004. Retinal involvement in dementia with Lewy bodies: A clue to hallucinations? Ann Neurol. 54(4):542-7.
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Snyder HM, Mensah K, Surgucheva I, Festoff B, Surguchov A, Wolozin B. 2005. b-Synuclein prevents proteasomal inhibition by α-synuclein but not γ-synuclein. J Biol Chem, 280(9):7562-9.
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Surgucheva, B. Yue, BC Park, S Tomarev and A. Surguchov. 2005. Interaction of myocilin with gamma-synuclein and its role in neurodegeneration in glaucoma. Cellular Molecular Neurobiology, 25, 6, 1009-1033.
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Surgucheva I, Ninkina N, Buchman VL, Grasing K, A. Surguchov. 2005. Protein aggregation in retinal cells and approaches to cell protection. Cellular Molecular Neurobiology, 25, 6, 1051-1066.
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