Dr. Yansheng Du

Indiana University School of Medicine, USA

Associate Professor

Email: ydu@iupui.edu

Qualifications

1988-1994 Ph.D, Wayne State University

1984-1987 M.S., Beijing Medical University

1978-1982 B.S., Beijing Normal University

Publications (selected)

1. Depboylu C, Behe M, Du Y, Noelker C, Staufenbiel M, Behr T, Henriksen G, Bacher M, Dodel R. Peripheral and central biodistribution of ¹¹¹In-labeled anti-beta-amyloid antibodies in a transgenic mouse model of Alzheimer's disease. Neurosci Lett. 2009 449(3): 240-5
2. Wei X, Du Z, Zhao L, Feng D, Wei G, He Y, Tan J, Lee WH, Hampel H, Dodel RC, Johnstone BH, March KL, Farlow MR, Du Y. The Conditioned Media of Adipose Stromal Cells Protect Against Hypoxia-Ischemia-Induced Brain Damage in Neonatal Rats. Stem Cells 2009 27(2): 478 – 488
3. Zhong J, Zhao L, Du Y, Wei G, Yao WG, Lee WH. Delayed IGF-1 treatment reduced long-term hypoxia–ischemia-induced brain damage and improved behavior recovery of immature rats. Neurological Research 2009 31(5): 483-9
4. Zhao L, Wei X, Ma Z, Feng D, Tu P, Johnstone BH, March KL, Du Y. Adipose stromal cells-conditional medium protected glutamate-induced CGNs neuronal death by BDNF. Neurosci Lett. 2009  452(3): 238-40.
5. Hou Y, Shao W, Xiao R, Xu K, Ma Z, Johnstone BH, Du Y. Pu-erh tea aqueous extracts lower atherosclerotic risk factors in a rat hyperlipidemia model. Exp Gerontol. 2009 44(6-7): 434-9.
6. Wei X, Zhao L, Zhong J, Feng D, Johnstone BH, March KL, Du Y. Adipose Stromal Cells-secreted Neuroprotective Media Against Neuronal Apoptosis. Neurosci Lett. 2009  462, 76–79.
7. Dodel R, Spottke A, Gerhard A, Reuss A, Reinecker S, Schimke N, Trenkwalder C, Sixel-Döring F, Herting B, Kamm C, Gasser T, Sawires M, Geser F, Köllensperger M, Seppi K, Kloss M, Krause M, Daniels C, Deuschl G, Böttger S, Naumann M, Lipp A, Gruber D, Kupsch A, Du Y, Turkheimer F, Brooks DJ, Klockgether T, Poewe W, Wenning G, Schade-Brittinger C, Oertel WH, Eggert K. Minocycline 1-year therapy in multiple-system-atrophy: Effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Mov Disord.. 2010 25(1): 97-107
8. Dodel R, Neff F, Noelker C, Pul R, Du Y, Bacher M, Oertel W. Intravenous immunoglobulins as a treatment for Alzheimer's disease: rationale and current evidence. Drugs. 2010 70(5): 513-28.
9. Behl M, Zhang Y, Shi Y, Cheng J, Du Y, Zheng W. Lead-Induced Accumulation of beta-Amyloid in the Choroid Plexus: Role of Low Density Lipoprotein Receptor Protein-1 and Protein Kinase C. Neurotoxicology. 2010 31(5): 524-32
10. Gu H, Wei X, Monnot AD, Fontanilla CV, Behl M, Farlow MR, Zheng W, Du Y. Lead exposure increases levels of β-amyloid in the brain and CSF and inhibits LRP1 expression in APP transgenic mice. Neurosci Lett. 2011 490(1): 16-20.
11. Dodel R, Balakrishnan K, Keyvani K, Deuster O, Neff F, Andrei-Selmer LC, Röskam S, Stüer C, Al-Abed Y, Noelker C, Balzer-Geldsetzer M, Oertel W, Du Y, Bacher M. Naturally Occurring Autoantibodies against {beta}-Amyloid: Investigating Their Role in Transgenic Animal and In Vitro Models of Alzheimer's Disease. J Neurosci. 2011 31(15): 5847-5854.
12. Tan B, Luan Z, Wei W, He Y, Wei G, Johnstone BH, Farlow M, and Du Y. AMPK Mediates Adipose Stem Cell-Stimulated Neuritogenesis of PC12 Cells. Neuroscience 2011 181: 40–47
13. Fontanilla C, Ma Z, Wei X, Klotsche J, Zhao L, Wisniowski P, Dodel RC, Farlow FR,  Oertel WH, Du Y. Caffeic Acid Phenethyl Ester Prevents 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Neurodegeneration. Neuroscience 2011, 188: 135–141
14. Gu H, Wei X, Chen S, Kurz A, Müller E, Gasser T, Dodel RC, Farlow MR and Du Y. Association of the Clusterin Gene Polymorphisms with Late-Onset Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders 2011, 32: 198-201
15. Fontanilla CV, Wei X, Zhao L, Johnstone B, Pascuzzi RM, Farlow MR, Du Y. Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis. Neuroscience. 2011 205: 185-93
16. Wei X, Roettger Y, Tan B, He Y, Dodel R, Hampel H, Wei G, Haney J, Gu H, Johnstone BH, Farlow MR, Du Y. Human anti-prion antibodies block prion peptide fibril formation and neurotoxicity. J Biol Chem. 2012, 287(16): 12858-66
17. Gu H, Robison G, Hong L, Barrea R, Wei X, Farlow MR, Pushkar YN, Du Y, Zheng W. Increased β-Amyloid Deposition in Tg-SWDI Transgenic Mouse Brain Following In Vivo Lead Exposure. Toxicol Lett. 2012, 213: 211-219

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