Biography

Dr. Germán Eduardo Piñas

School of Biological Sciences

University of Utah, USA

Research Assistant Professor


Email: g.pinas@utah.edu


Qualifications

2008 Ph.D., National University of Cordoba, Argentina

2002 B.S. and M.S., National University of Cordoba, Argentina


Publications (Selected)


  1. Reinoso-Vizcaino, N.M., Cian, M.B., Cortes, P.R., Olivero, N.B., Hernandez-Morfa, M., Pinas, G.E., Badapanda, C., Rathore, A., Perez, D.R., and Echenique, J. The pneumococcal two-component system SirRH is linked to enhanced intracellular survival of Streptococcus pneumoniae in influenza-infected pulmonary cells.  PLoS Pathog 14: e1007118. 2020 (in press).
  2. Pinas, G.E. and Parkinson, J.S. Identification of a Kinase-Active CheA Conformation in Escherichia coli Chemoreceptor Signaling Complexes. J Bacteriol  201(23).2019 
    https://jb.asm.org/content/early/2019/09/05/JB.00543-19
    Highlighted as a top-article in Journal of Bacteriology’s Spotlight Section.
  3. Pinas, G.E., Reinoso-Vizcaino, N.M., Yandar Barahona, N.Y., Cortes, P.R., Duran, R., Badapanda, C., Rathore, A., Bichara, D.R., Cian, M.B., Olivero, N.B., Perez, D.R., and Echenique, J. Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae. PLoS Pathog 14: e1007118. 2018.  https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007118
  4. Pinas, G.E., DeSantis, M.D., and Parkinson, J.S. Noncritical Signaling Role of a Kinase-Receptor Interaction Surface in the Escherichia coli Chemosensory Core Complex. J Mol Biol 430: 1051-1064. 2018.
    https://www.sciencedirect.com/science/article/pii/S0022283618300743
  5. Frank, V., Pinas, G.E., Cohen, H., Parkinson, J.S., and Vaknin, A. Networked Chemoreceptors Benefit Bacterial Chemotaxis Performance. MBio 7. 2016.
    https://mbio.asm.org/content/7/6/e01824-16
  6. Pinas, G.E., Frank, V., Vaknin, A., and Parkinson, J.S. The source of high signal cooperativity in bacterial chemosensory arrays. Proc Natl Acad Sci U S A 113: 3335-3340. 2016.
    https://www.pnas.org/content/113/12/3335.long
  7. Cortes, P.R., Pinas, G.E.*, Cian, M.B., Yandar, N., and Echenique, J. Stress-triggered signaling affecting survival or suicide of Streptococcus pneumoniae. Int J Med Microbiol 305: 157-169. 2015. * Shared first-authorship
    https://www.sciencedirect.com/science/article/abs/pii/S1438422114001611?via%3Dihub
  8. Albarracin Orio, A.G., Pinas, G.E., Cortes, P.R., Cian, M.B., and Echenique, J. Compensatory evolution of pbp mutations restores the fitness cost imposed by beta-lactam resistance in Streptococcus pneumoniae. PLoS Pathog 7: e1002000. 2011.
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1002000
  9. Pinas, G.E., Cortes, P.R., Orio, A.G., and Echenique, J. Acidic stress induces autolysis by a CSP-independent ComE pathway in Streptococcus pneumoniae. Microbiology (SGM) 154: 1300-1308. 2008.
    https://mic.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.2007/015925-0#tab2
  10. Cortes, P.R., Pinas, G.E., Albarracin Orio, A.G., and Echenique, J.R. Subinhibitory concentrations of penicillin increase the mutation rate to optochin resistance in Streptococcus pneumoniae. J Antimicrob Chemother 62: 973-977. 2018.

    https://academic.oup.com/jac/article/62/5/973/727648

  11. Cortes, P.R., Orio, A.G., Regueira, M., Pinas, G.E., and Echenique, J. Characterization of in vitro-generated and clinical optochin-resistant strains of Streptococcus pneumoniae isolated from Argentina. J Clin Microbiol 46: 1930-1934. 2008.

    https://jcm.asm.org/content/46/6/1930
  12. Albarracin Orio, A.G., Cortes, P.R., Tregnaghi, M., Pinas, G.E., Argentinean Network Pneumococcus Study Group, and Echenique, J.R. A new serotype 14 variant of the pneumococcal Spain9V-3 international clone detected in the central region of Argentina. J Med Microbiol 57: 992-999. 2008.

    https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.2008/000505-0#tab2




Profile Details   

Last Updated: July, 2020


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