This book is based on a partial fulfillment of my doctoral thesis, which was finished about 20 years ago.
This book is composed of 7 chapters. In the present work, the author is trying to describe his contribution to the chemistry of a fundamental unit reaction, bimolecular aromatic nucleophilic substitution (SNAr) reaction, with the hope of leaving something for the welfare of the human being.
Sample Chapter(s)
Foreword (178 KB)
Components of the Book:
- Author Profile
- Foreword
- Chapter 1. Introduction
- 1.1. SN1 Mechanism
- 1.2. Benzyne or Elimination-Addition Mechanism
- 1.3. Bimolecular Addition-Elimination (SNAr) Mechanism
- Chapter 2. Present Status of the Mechanisms of Bimolecular SNAr Reaction
- 2.1. Steady-State Mechanism
- 2.2. Dimer Nucleophile Mechanism
- 2.3. Molecular Complex Mechanism
- 2.4. Forced Desolvation Mechanism
- 2.5. SB-GA (Specific Base-General Acid) Mechanism
- 2.6. The Planning of the Present Studies
- Chapter 3. SNAr Reaction in a System of Least Solvation, Where Examination Is Feasible with Least Complication from Solute-Solvent Interaction. Rising Questions to the Prevailing Contemporary Mechanisms
- 3.1. Reaction System and Kinetic Results
- 3.2. Discussions
- Chapter 4. SNAr Reaction in the Conventional Solvent, Questions Are Verified in a Popular Reaction System
- 4.1. Reaction System and Kinetic Results
- 4.2. Discussions
- Chapter 5. Direct Comparison with Forerunners. Failure of the Contemporary Mechanisms and the New Aspects of the Time-Honored Reaction
- 5.1. Reaction System and Kinetic Results
- 5.2. Discussions
- Chapter 6. Conclusions and Prospects
- Chapter 7. Experiments
- 7.1. Apparatus
- 7.2. Solvents
- 7.3. Reagents
- 7.4. Products
- 7.5. Kinetic Measurements
- 7.6. Control Experiments in the Reaction of PicF with Quinuclidine
- 7.7. Measurements by 1H-NMR Spectroscopy
- 7.8. Measurements by Vapor Pressure Osmometry
- 7.9. Measurements by Cryoscopic Method
- 7.10. Determination of Equilibrium Constants (For the Reaction of Picric Acid with Amines in Benzene)
- Reference
Readership:
Students, academics, teachers, and other people attending or interested in Chemistry of Aromatic Nucleophilic Substitution Reaction in Solvents of Low Relative Permittivity.
Li-Quan Sun
Associate professor of the School of Life Science in Beijing Institute of Technology, China.