Kumari Bairwa, R. and Shukla, C. (2020) Comparison of Administration of Intraperitoneal Bupivacaine and Intraperitoneal Bupivacaine with Dexmedetomidine in Post Laparoscopic Cholecystectomy Patients for Post Operative Pain Relief. Indian Journal of Clinical Anaesthesia, 5, 561-565.
https://doi.org/10.18231/2394-4994.2018.0106

has been cited by the following article:

• TITLE: Intraperitoneal Instillation of Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine for Postoperative Pain in Laparoscopic Cholecystectomy, a Randomized Clinical Trial

  AUTHORS: Ayman Mohamady Eldemrdash, Zaher Z. Zaher, Tarek S. Hemaida, Taha T. Dardeer, Hani M. Raslan, Shawky M. Abdelgalil, Mohmed R. Saad, Mohammed S. Aly

  KEYWORDS: Bupivacaine, Dexmedetomidine, Dexamethasone, Laparoscopic Cholecystectomy

  JOURNAL NAME: Open Journal of Anesthesiology, Vol.15 No.1, January 24, 2025

  ABSTRACT: Background: Intraperitoneal instillation (IPI) of local anesthesia was reported to reduce postoperative pain after laparoscopic surgeries. We aim to evaluate the effectiveness of IPI of bupivacaine + dexmedetomidine versus bupivacaine + dexamethasone on postoperative pain in patients undergoing laparoscopic cholecystectomy (LC). Methods: This randomized clinical trial was carried out on one hundred patients who underwent LC under general anesthesia. Patients were randomly divided into: Group (Dexa): IPI of bupivacaine with dexamethasone and Group (Dexmed): IPI of bupivacaine with dexmedetomidine. Results: The first time to request analgesia was significantly delayed in the dexmed group (P value Conclusions: Intraperitoneal Bupivacaine + Dexmedetomidine provided longer pain-free postoperative duration lower pain score over time, and lesser analgesic consumption.