TITLE:
Re-Evaluation of the Safety of Laser-Assisted Subepithelial Keratectomy
AUTHORS:
Yuji Kumano, Yumi Soejima, Shinichiro Numa, Hiroyasu Matsui, Ikuko Zushi, Masahito Shigematsu, Takaaki Matsui, Teruo Nishida
KEYWORDS:
BSCVA, LASEK, Loss of Two or More Lines, Preoperative Myopia, Re-Evaluation
JOURNAL NAME:
Open Journal of Ophthalmology,
Vol.4 No.3,
August
13,
2014
ABSTRACT:
Purpose: Additional analyses of outcomes of laser-assisted subepithelial
keratectomy (LASEK) are still necessary to improve the safety of LASEK.
Therefore, in our study, outcomes were assessed retrospectively in 561 eyes
that underwent LASEK treatment. Methods: Uncorrected visual acuity (UCVA), best
spectacle-corrected visual acuity (BSCVA) and residual spherical equivalent
were analyzed at 3 and 6 months postoperatively. We assessed four subgroups
based on the degree of preoperative myopia considering mean BSCVA and loss of
two or more lines. Results: Mean UCVAs and BSCVAs were obtained at 3 and 6
months postoperatively (1.23/1.35 and 1.23/1.37, respectively). The mean
predictability was within ±0.125 diopters. Conversely, the safety indexes were
0.94 and 0.96 respectively, and the efficacy indexes were 0.86 and 0.86 at 3
and 6 months postoperatively, respectively. 8.4% eyes and 5.2% eyes lost two or
more lines of BSCVA at 3 and 6 months postoperatively, respectively. The mean
BSCVAs of the high or ultra-high groups were significantly lower than those of
the low or mild groups both 3 months and 6 months postoperatively. The
incidence rates of losing two or more lines of BSCVA in the high or ultra-high
myopia groups were significantly greater than in the low or mild groups at 3
months and 6 months postoperatively. Conclusion: LASEK predictably corrected
myopia achieving >1.2 in UCVA and BSCVA. However, the safety and efficacy
indexes were