Fuzzy Cluster Analysis of Alzheimer’s Disease-Related Gene Sequences

Jing Yang, Jiarui Si, Xiaoxuan Gu, Ouyan Shi

School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
School of Public Health, Tianjin Medical University, Tianjin, China.

DOI: 10.4236/eng.2013.510B109                

Abstract

The objective of this paper is to analyze the relationship among the interrelated gene sequences of Alzheimer’s disease (AD). Further this paper will provide a study on genetic factor of the occurrence about Alzheimer’s disease, so as to provide more information on the prevention of Alzheimer’s disease, the clinical diagnosis and gene therapy for Alzheimer’s disease. The respective alignment of the Alzheimer’s disease interrelated gene sequences with those in The National Center for Biotechnology Information (NCBI) database was studied, and the measurement relationship of these sequences was identified and analyzed by the method of fuzzy cluster. The result of fuzzy cluster analysis indicates that the gene sequences interrelated within one group is consistently having closer relationship within the group other than in another group.

Keywords

Alzheimer’s Disease; Gene; mRNA; Sequence; Alignment; Fuzzy Cluster

Conflicts of Interest

The authors declare no conflicts of interest.

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