The Determination of Surface Tension of Traditional Chinese Medicine Tablet

Xiaolu Zhang, Hao Zhang, Ke Liang, Er’jia Zhu, Ruisi Yan, Hui Yang, Zaiyou Tan

School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.

DOI: 10.4236/jmp.2012.312236                

Abstract

In this paper we aimed to determine the surface tension of traditional Chinese medicine (TCM) tablet and tried to provide a key reference parameter to control tablet film coating quality. Using contact angle tester, the Chinese medicine tablet, a famous Fufang Danshen tablet CP as a model example, was determined by Zisman critical surface tension method. Our study showed that the critical surface tension of Fufang Danshen tablet CP was determined to be 18.00 dyne/cm. The Zisman method, hence, can determine successfully the critical surface tension of Chinese medicine tablet and will become an effective manner to control tablet film coating quality.

Keywords

Surface Tension; Contact Angle; The Zisman Critical Surface Tension Method; Fufang Danshen Tablet CP; Chinese Medicine

Conflicts of Interest

The authors declare no conflicts of interest.

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