Dr. Yasumasa Okada

Division of Internal Medicine and Laboratory of Electrophysiology

Murayama Medical Center, Japan

Associate Professor

Email: yasumasaokada@1979.jukuin.keio.ac.jp

Qualifications

1987 Ph.D.,Keio University, Japan

1983 M.Sc., Keio University, Japan

1979 B.Sc., Keio University, Japan

Publications (selected)

1. Hasebe, Yohei & Yokota, Shigefumi & Fukushi, Isato & Takeda, Kotaro & Yoshizawa, Masashi & Onimaru, Hiroshi & Kono, Yosuke & Sugama, Shuei & Uchiyama, Makoto & Koizumi, Keiichi & Horiuchi, Jouji & Kakinuma, Yoshihiko & Pokorski, Mieczyslaw & Toda, Takako & Izumizaki, Masahiko & Mori, Yasuo & Sugita, Kanji & Okada, Yasumasa. (2024). Persistence of post-stress blood pressure elevation requires activation of astrocytes. Scientific Reports. 14. 10.1038/s41598-024-73345-4.

2. Fukushi, Isato & Yokota, Shigefumi & Hasebe, Yohei & Pokorski, Mieczyslaw & Okada, Yasumasa. (2024). Modulation of respiration and hypothalamus. 10.1016/bs.vh.2024.06.006.

3. Onimaru, Hiroshi & Fukushi, Isato & Ikeda, Keiko & Yazawa, Itaru & Takeda, Kotaro & Okada, Yasumasa & Izumizaki, Masahiko. (2023). Cell Responses of the Ventrolateral Medulla to PAR1 Activation and Changes in Respiratory Rhythm in Newborn Rat En Bloc Brainstem-Spinal Cord Preparations. Neuroscience. 528. 10.1016/j.neuroscience.2023.08.002.

4. Umeda, Akira & Shimada, Hisato & Yamane, Tateki & Mochizuki, Taichi & Inoue, Yasushi & Tsushima, Kenji & Miyagawa, Kazuya & Mochida, Atsumi & Takeda, Hiroshi & Okada, Yasumasa & Masaki, Katsunori & Matsusaka, Masako & Fukunaga, Koichi. (2023). Real-world effects of once-daily inhaled steroid (fluticasone furoate) combined with long-acting beta-2 agonist (vilanterol) and long-acting muscarinic antagonist (umeclidinium) on lung function tests of asthma patients in Japan. Frontiers in Physiology. 14. 10.3389/fphys.2023.1131949.

5. Fukushi, Isato & Ikeda, Keiko & Takeda, Kotaro & Yoshizawa, Masashi & Kono, Yosuke & Hasebe, Yohei & Pokorski, Mieczyslaw & Okada, Yasumasa. (2023). Minocycline prevents hypoxia-induced seizures. Frontiers in neural circuits. 17. 1006424. 10.3389/fncir.2023.1006424.                                                               

6. Umeda, Akira & Miyagawa, Kazuya & Mochida, Atsumi & Takeda, Hiroshi & Ohira, Yoshiyuki & Kato, Toru & Okada, Yasumasa & Kotani, Kazuhiko. (2022). Effects of smoking cessation using varenicline on the serum concentrations of oxidized high-density lipoprotein: Comparison with high-density lipoprotein cholesterol. PLOS ONE. 17. e0277766. 10.1371/journal.pone.0277766.

7. Komiyama, Maki & Ozaki, Yuka & Wada, Hiromichi & Yamakage, Hajime & Satoh-Asahara, Noriko & Yasoda, Akihiro & Sunagawa, Yoichi & Morimoto, Tatsuya & Tamaki, Shinji & Masahiro Suzuki, & Shibayama, Takuo & Kato, Toru & Okada, Yasumasa & Kita, Toshiyuki & Takahashi, Yuko & Hasegawa, Koji. (2022). Randomized double-blind placebo-controlled multicenter trial for the effects of a polyherbal remedy, Yokukansan (YiganSan), in smokers with depressive tendencies. BMC Complementary Medicine and Therapies. 22. 10.1186/s12906-022-03788-7.

8. Yoshizawa, Masashi & Fukushi, Isato & Takeda, Kotaro & Kono, Yosuke & Hasebe, Yohei & Koizumi, Keiichi & Ikeda, Keiko & Pokorski, Mieczyslaw & Toda, Takako & Okada, Yasumasa. (2022). Role of microglia in blood pressure and respiratory responses to acute hypoxic exposure in rats. The journal of physiological sciences : JPS. 72. 26. 10.1186/s12576-022-00848-y.

9. Fukushi, Isato & Yokota, Shigefumi & Takeda, Kotaro & Terada, Jiro & Umeda, Akira & Yoshizawa, Masashi & Kono, Yosuke & Hasebe, Yohei & Onimaru, Hiroshi & Pokorski, Mieczyslaw & Okada, Yasumasa. (2022). Dual orexin receptor blocker suvorexant attenuates hypercapnic ventilatory augmentation in mice. Brain Research. 1795. 148061. 10.1016/j.brainres.2022.148061.

10. Orsi Barioni, Nicole & Derakhshan, Fatemeh & Tenorio Lopes, Luana & Onimaru, Hiroshi & Roy, Arijit & Mcdonald, Fiona & Scheibli, Erika & Baghdadwala, Mufaddal & Heidari, Negar & Bharadia, Manisha & Ikeda, Keiko & Yazawa, Itaru & Okada, Yasumasa & Harris, Michael & Dutschmann, Mathias & Wilson, Joanne. (2022). Novel oxygen sensing mechanism in the spinal cord involved in cardiorespiratory responses to hypoxia. Science Advances. 8. 10.1126/sciadv.abm1444.

11. Yazawa, Itaru & Okazaki, Shuntaro & Yokota, Shigefumi & Takeda, Kotaro & Fukushi, Isato & Yoshizawa, Masashi & Onimaru, Hiroshi & Okada, Yasumasa. (2021). Coherence analysis of the calcium activity of putative astrocytic and neuronal cells on the L5 ventral horn and neural output in activated lumbar CPG networks. Neuroscience Letters. 771. 136421. 10.1016/j.neulet.2021.136421.

12. Okada, Yasumasa & Paton, Julian & López-Barneo, José & Wilson, Richard & Marina, Nephtali & Pokorski, Mieczyslaw. (2021). Editorial: Hypoxia and Cardiorespiratory Control. Frontiers in Physiology. 12. 10.3389/fphys.2021.820815.

13. Mochida, Atsumi & Miyagawa, Kazuya & Kimijima, Hidenao & Miyagishi, Hiroko & Kurokawa, Kazuhiro & Tsuji, Minoru & Umeda, Akira & Okada, Yasumasa & Takeda, Hiroshi. (2021). -YIA-01 Genetical and pharmacological inhibition of ATP-sensitive potassium channels induces anxiety-like behavior in mice Young Investigator Outstanding Oral Presentation Award Sessions (YIA) Proceedings for The 92nd Annual Meeting of the Japanese Pharmacological Society.

14. Fukushi, Isato & Takeda, Kotaro & Pokorski, Mieczyslaw & Kono, Yosuke & Yoshizawa, Masashi & Hasebe, Yohei & Nakao, Akito & Mori, Yasuo & Onimaru, Hiroshi & Okada, Yasumasa. (2021). Activation of Astrocytes in the Persistence of Post-hypoxic Respiratory Augmentation. Frontiers in Physiology. 12. 757731. 10.3389/fphys.2021.757731.

15. Umeda, Akira & Ishizaka, Masahiro & Ikeda, Akane & Miyagawa, Kazuya & Mochida, Atsumi & Takeda, Hiroshi & Takeda, Kotaro & Fukushi, Isato & Okada, Yasumasa & Gozal, David. (2021). Recent Insights into the Measurement of Carbon Dioxide Concentrations for Clinical Practice in Respiratory Medicine. Sensors. 21. 5636. 10.3390/s21165636.

16. Onimaru, Hiroshi & Yazawa, Itaru & Takeda, Kotaro & Fukushi, Isato & Okada, Yasumasa. (2021). Calcium Imaging Analysis of Cellular Responses to Hypercapnia and Hypoxia in the NTS of Newborn Rat Brainstem Preparation. Frontiers in Physiology. 12. 10.3389/fphys.2021.645904.

17. Hiraishi, Keizo & Lin, Hai & Feng, Jianlin & Hotta, Aya & Cui, Yuanyuan & Yahiro, Eiji & Yokomise, Hiroyasu & Go, Tetsuhiko & Ishikawa, Kaori & Yokota, Naoya & Fujiwara, Atsushi & Onitsuka, Miki & Abe, Kohtaro & Ohga, Shoji & Satoh, Toru & Okada, Yasumasa & Yue, Lixia & Inoue, Ryuji & Hirano, Katsuya. (2021). Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension. Translational Research. 233. 10.1016/j.trsl.2021.03.004.

18. Fukushi, Isato & Pokorski, Mieczyslaw & Okada, Yasumasa. (2020). Mechanisms underlying the sensation of dyspnea. Respiratory Investigation. 59. 10.1016/j.resinv.2020.10.007.

19. Umeda, Akira & Miyagawa, Kazuya & Mochida, Atsumi & Takeda, Hiroshi & Takeda, Kotaro & Okada, Yasumasa & Gozal, David. (2020). Effects of Normoxic Recovery on Intima-Media Thickness of Aorta and Pulmonary Artery Following Intermittent Hypoxia in Mice. Frontiers in Physiology. 11. 10.3389/fphys.2020.583735.

20. Kono, Yosuke & Yokota, Shigefumi & Fukushi, Isato & Arima, Yosuke & Onimaru, Hiroshi & Okazaki, Shuntaro & Takeda, Kotaro & Yazawa, Itaru & Yoshizawa, Masashi & Hasebe, Yohei & Koizumi, Keiichi & Pokorski, Mieczyslaw & Toda, Takako & Sugita, Kanji & Okada, Yasumasa. (2020). Structural and functional connectivity from the dorsomedial hypothalamus to the ventral medulla as a chronological amplifier of sympathetic outflow. Scientific Reports. 10. 10.1038/s41598-020-70234-4.

Profile Details

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