TITLE:
How different is early-onset childhood disintegrative disorder from autistic disorder with speech loss?
AUTHORS:
Hiroshi Kurita, Kanna Inoue
KEYWORDS:
Autistic Disorder; Autism Spectrum Disorder (ASD); Childhood Disintegrative Disorder; Diagnosis; Regression
JOURNAL NAME:
Open Journal of Psychiatry,
Vol.3 No.2A,
April
16,
2013
ABSTRACT:
To examine the difference between early-onset (with early-onset CDD
(mean age = 7.6 years, SD = 3.8; 6 males) were compared with 92 age and
gender-ratio comparable children with ADSL (mean age = 6.8 years, SD = 4.1; 70
males) on 24 variables not directly related to the key features of CDD
(regression after normal development for at least the first 2 years after birth).
Compared with the ADSL group, the early-onset CDD group had a tendency to have
a higher rate of a psychosocial event before speech loss (SL) (early-onset CDD,
75.0% vs ADSL, 37.0%, p = 0.057; effect size (phi) = 0.211, p 0.050; phi = 0.271, p rate of the Childhood Autism Rating Scale-Tokyo Version (CARS-TV)
total score ≥ 30 (75.0% vs 95.7%, p = 0.072; phi = 0.236, p ity of the 24
variables between the two groups support integrating CDD into regressive
autism spectrum disorder and studying CDD as its prototypical form.