TITLE:
Place of Seminal Biochemical Markers in the Etiological Diagnosis of Azoospermia in Cotonou in 2023
AUTHORS:
Simon Azonbakin, David Houndetoungan, Yasmine Madohonan, Jean Sossa, Etienne Goulai Bi, Essi N’bouke, Godwin Soglo, Marius Adjagba, Jean Paul Dossou, Anatole Laleye
KEYWORDS:
Azoospermia, Seminal Fluid, Biochemical Markers, Benin
JOURNAL NAME:
Advances in Reproductive Sciences,
Vol.13 No.1,
February
28,
2025
ABSTRACT: Azoospermia, defined as a complete absence of spermatozoa in the ejaculate, is a relatively common condition among infertile men. Establishing the etiological diagnosis can be challenging and often requires various investigations. This cross-sectional study, conducted in Cotonou among 35 azoospermic men, aimed to assess the role of biochemical analysis of seminal fluid in determining the etiological diagnosis. The results revealed significant heterogeneity in biochemical profiles. Most of the patients had normal levels of alpha-glucosidase, fructose, and zinc, indicating normal accessory gland function and suggesting non-obstructive azoospermia. However, a significant subgroup exhibited abnormalities in these markers, suggesting a possible obstructive azoospermia. The heterogeneity in biochemical profiles observed in this study highlights the need for further studies to better characterize azoospermia in Benin.