TITLE:
The Role of T Lymphocyte Subsets in Breast Cancer
AUTHORS:
Qian Li, Guanming Lu
KEYWORDS:
Breast Cancer, Tumor Microenvironment, T Lymphocytes, Immune Cells
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.12 No.12,
December
12,
2024
ABSTRACT: Breast cancer, a leading type of malignant tumor, is highly heterogeneous, with each subtype having different prognoses and potential therapeutic targets. The tumor microenvironment plays a key role in tumor development. It consists of immune cells, stromal cells, the extracellular matrix, and blood and lymphatic networks, forming a complex immune regulatory network. In anti-tumor immunity, the cellular immune response led by T lymphocytes is crucial. An in-depth study of T lymphocytes in the tumor microenvironment may offer new insights for breast cancer treatment. This article reviews the role of T lymphocyte subsets in the current tumor microenvironment of breast cancer.