TITLE:
Asthma Attack Revealing Sickle Cell Disease
AUTHORS:
Khaoula Achir, Ilham Tadmori, Moustapha Hida
KEYWORDS:
Sickle Cell Disease, Asthma, Morbidity
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.14 No.5,
September
10,
2024
ABSTRACT: Sickle cell disease is a genetic disorder characterized by the presence of hemoglobin S (HbS) and a significant reduction in normal hemoglobin A (HbA) in red blood cells. In deoxygenated conditions, HbS molecules polymerize, causing vascular occlusions and hemolysis. Pulmonary complications associated with this disease result from vascular occlusion, ischemia-reperfusion, and inflammation. Literature reports that asthma is observed in 30% to 70% of patients with sickle cell disease. We present the case of a boy whose sickle cell disease diagnosis was established following an asthma attack.