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https://doi.org/10.1021/acs.jnatprod.8b00735

has been cited by the following article:

• TITLE: Natural Products and Antiviral Resistance

  AUTHORS: Erute Magdalene Adongbede, Janak Raj Khatiwada, Rishipal Rastrapal Bansode, Leonard Lamont Williams

  KEYWORDS: Drug Resistance, Resistance Mechanisms, Phytochemicals, Broad-Spectrum Drugs, Antiviral Agents

  JOURNAL NAME: Advances in Microbiology, Vol.14 No.7, July 31, 2024

  ABSTRACT: Viral diseases are minacious with the potential for causing pandemics and treatment is complicated because of their inherent ability to mutate and become resistant to drugs. Antiviral drug resistance is a persistent problem that needs continuous attention by scientists, medical professionals, and government agencies. To solve the problem, an in-depth understanding of the intricate interplay between causes of antiviral drug resistance and potential new drugs specifically natural products is imperative in the interest and safety of public health. This review delves into natural product as reservoir for antiviral agents with the peculiar potentials for addressing the complexities associated with multi-drug resistant and emerging viral strains. An evaluation of the mechanisms underlying antiviral drug activity, antiviral drug resistance is addressed, with emphasis on production of broad-spectrum antiviral agents from natural sources. There is a need for continued natural product-based research, identification of new species and novel compounds.