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has been cited by the following article:

• TITLE: Phytochemical Analysis and Antioxidant Activity of Aqueous and Hydroethanolic Extracts from Three Anticancerous Fabaceae of Northern Cameroon Pharmacopoeia

  AUTHORS: Halmata Mohamadou, Landry Lienou Lienou, Richard Simo Tagne, Herve Pabamé Kada, Elisee Libert Enyengue Embolo, Grace Kembaou Nganwa, Jean Louis Oyono Essame, Piere Michel Dongmo Jazet

  KEYWORDS: Cancer, Antioxidant, Fabaceae, Phenolic Compounds, Aqueous Extract, Hydroethanolic Extract

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.12 No.6, June 7, 2024

  ABSTRACT: Background: Cancer continues to pose a significant threat to our society, representing one of the most pressing health concerns worldwide. This study aimed to evaluate the chemical composition and the antioxidant activity of aqueous and hydroethanolic extracts from Acacia nilotica (An), Bauhinia reticulate (Br), and Tamarindus indica (Ti) of Fabaceae family, traditionally used in Northern Cameroon for cancer treatment. Methods: The phytochemical screening of the three plants was conducted using conventional colorimetric methods, followed by the measurement of total phenol content, flavonoids, and tannins. The antiradical and antioxidant activities of both plant extracts were assessed through FRAP, ABTS, and DPPH methods. A principal components analysis was employed to correlate the quantities of the evaluated secondary metabolites with the activities. Results: Both types of extracts from the three plants contain alkaloids, saponins, flavonoids, phenolic compounds, tannins, glycosides, terpenoids, coumarins, anthocyanins, and anthraquinones. The aqueous extracts of Br and An are significantly richer (p Conclusion: The three Fabaceae plants from northern Cameroon, prepared in different solvents, can be utilized for their antiradical properties in cancer treatment.