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has been cited by the following article:

• TITLE: Dual Treatment Strategy by Venous Ulcers: Pilot Study to Dual-Frequency Ultrasound Application

  AUTHORS: Ilja Kruglikov, Ekaterina Kruglikova

  KEYWORDS: Venous Ulcer, Dual-Frequency Ultrasound, Matrix Metalloproteinases, Heat Shock Proteins

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.1 No.4, December 1, 2011

  ABSTRACT: We propose a new dual treatment strategy by venous ulcer, consisting in simultaneous modulation of matrix metalloproteinases (MMPs) and heat shock proteins (HSPs) in the wound. One treatment method which can efficiently modulate both these substances is based on the application of dual-frequency ultrasound (LDM). This strategy was checked in a pilot study on 10 patients with chronic venous ulcers and demonstrated excellent healing rate.