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has been cited by the following article:

• TITLE: Spontaneous Heparin-Induced Thrombocytopenia Following Orthopaedic Surgery: Case Report and Review of the Literature

  AUTHORS: Malcolm R. DeBaun, Michael A. Spinner, Michael D. Genualdi, Caroline Berube, Derek F. Amanatullah

  KEYWORDS: Spontaneous Heparin Induced Thrombocytopenia, HIT, Arthroplasty, Total Knee Arthroplasty, TKA

  JOURNAL NAME: Open Journal of Orthopedics, Vol.7 No.12, December 5, 2017

  ABSTRACT: Background: Spontaneous heparin induced thrombocytopenia (HIT) is a medical phenomenon whereby patients develop clinical and laboratory features of HIT without prior exposure to heparin. Aim: We present a patient who underwent bilateral total knee replacement complicated by spontaneous HIT causing bilateral adrenal hemorrhage and deep vein thrombosis. Our patient had no prior history of heparin exposure. We reconcile our patient’s presentation with other case reports of spontaneous HIT in patients who had orthopaedic surgery. Conclusion: Spontaneous HIT is a rare but potentially devastating complication associated with total knee arthroplasty.