Llovet, J.M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J.F., de Oliveira, A.C., Santoro, A., Raoul, J.L., Forner, A., Schwartz, M., Porta, C., Zeuzem, S., Bolondi, L., Greten, T.F., Galle, P.R., Seitz, J.F., Borbath, I., H?ussinger, D., Giannaris, T., Shan, M., Moscovici, M., Voliotis, D. and Bruix, J., SHARP Investigators Study Group (2008) Sorafenib in Advanced Hepatocellular Carcinoma. New England Journal of Medicine, 359, 378-390.
http://dx.doi.org/10.1056/NEJMoa0708857

has been cited by the following article:

• TITLE: Successful Surgical Treatment of Metachronous Oligometastases from Non-B, Non-C Hepatocellular Carcinoma

  AUTHORS: Haruchika Yamamoto, Yuji Hirami, Tomohiro Toji, Yoko Shinno, Tetsuya Ota, Minoru Naito, Akio Andou

  KEYWORDS: Hepatocellular Carcinoma, Mediastinal Metastases, Rib Metastases, Oligometastases

  JOURNAL NAME: Open Journal of Thoracic Surgery, Vol.6 No.2, May 31, 2016

  ABSTRACT: Hepatocellular Carcinoma (HCC) rarely metastasizes to bone or mediastinum. In some patients, surgical treatment of oligometastatic lesions from colorectal cancer, breast cancer, or non-small cell lung cancer results in satisfactory survival. However, data concerning oligometastatic lesions from HCC are scarce. We report the case of a patient with long-term survival after resection of metachronous oligometastases of HCC. A 54-year-old woman underwent hepatic resection for non-B, non-C HCC. A solitary left tenth rib tumor was detected 20 months after initial surgery and was surgically resected. A solitary mediastinal tumor was detected 6 months after the second operation and the patient again underwent surgical resection. Histopathological examination of both lesions confirmed metastasis of HCC. The patient has had no further recurrence 7 years after initial surgery without chemotherapy or radiotherapy.