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has been cited by the following article:

• TITLE: The Role of Gut Microbiota in the Mechanism of Cognitive Impairment in the Elderly

  AUTHORS: Xurui Li, Yanpeng Li, Zhichao Ma, Jianguo Li

  KEYWORDS: Alzheimer’s Disease, Cognitive Impairment, Gut Microbiota, Gut Microbiota-Brain Axis

  JOURNAL NAME: Open Journal of Modern Neurosurgery, Vol.12 No.4, October 20, 2022

  ABSTRACT: With the aging in whole world, it has become a great challenge to explore the relationship between the cognitive and behavioral performance of senile dementia and the underlying pathology of the brain. Alzheimer’s disease (AD) is a common age-related and progressive neurodegenerative disease characterized and one of the main causes of senile dementia. The pathogenesis and treatment mechanism of AD are not completely clear. In recent years, it has been found that the Gut microbiota (GM) disorder is related to nervous system diseases. The objective of this review is to summarize the etiology and pathogenyon the role of GM in the development of AD, metabolites of GM and the occurrence of AD, and GM, diabetes and occurrence of AD. Understanding the relationship between GM and AD will help provide possible interventions to improve the structure of GM and prevent AD through different treatments, and it may provide clinicians with a new and more effective way for early diagnosis, prevention and treatment of AD.