TITLE:
Ultrasonic Activation of Suzuki and Hiyama Cross-Coupling Reactions Catalyzed by Palladium
AUTHORS:
Khemais Said, Ridha Ben Salem
KEYWORDS:
Palladium, Suzuki Cross-Coupling, Hiyama, Ultrasound, Sonochemical Activation
JOURNAL NAME:
Advances in Chemical Engineering and Science,
Vol.6 No.2,
April
14,
2016
ABSTRACT: The coupling reaction of
aryl bromide and aryl boronic acid in water/DMF as solvent was studied using a
palladium-complex as a catalyst in the presence of ultrasound at room
temperature. The effect on the reaction of a base and a solvent was also
studied with and without ultrasound and was found to increase the speed of the
reaction. In this regard, we propose reaction mechanisms that could explain the
results obtained.