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has been cited by the following article:

• TITLE: Rapid Determination of Residual Quinolones in Honey Samples by Fast HPLC with an On-Line Sample Pretreatment System

  AUTHORS: Wei Du, JianGuo Yao, YueQi Li, Yuki Hashi

  KEYWORDS: Antibiotics, High Performance Liquid Chromatography (HPLC), Honey; On-Line Pretreatment, Quinolones

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.2 No.2, May 30, 2011

  ABSTRACT: A method of on-line pretreatment coupled to HPLC with fluorescence detection was developed and validated for the determination of nine quinolones in honey samples. This method simplified the complicated process of sample pretreatment and reduced sample treatment time. Recovery of the quinolones was between 92% - 101% for spiked honey samples. The limit of detection was 0.22 - 3.78 ng/mL (signal/noise ratio = 3). There was good linear correlation between HPLC peak area and concentration of the quinolones, with a linear range of 1.0 - 100.0 ng/mL and correlation coefficients >0.9997. The method proposed was validated for detecting quinolones in honey samples.