TITLE:
AML presenting as a mediastinal mass and right ventricular failure
AUTHORS:
Jeremy B. Moad, Kellie R. Jones
KEYWORDS:
Granulocytic Myeloid Sarcoma; Myeloid Sarcoma; Right Heart Failure; Pulmonary Artery Stenosis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.2 No.1,
March
22,
2013
ABSTRACT:
Extrinsic compression
of the pulmonary arteries by mediastinal masses, while rare, is the most common cause of non-congenital peripheral pulmonary artery stenosis. Granulocytic myeloid sarcomas are an extramedullary manifestation
of acute myeloid leukemia, with a wide variability in their presentation. They
can present either de novo as soft tissue masses or in conjunction
with acute myeloid leukemia. Myeloid sarcomas are uncommon and their prognosis is
generally considered poor when present in patients with acute myeloid leukemia (AML).
We present a case of a granulocytic myeloid sarcoma causing pulmonary artery stenosis
and right ventricular failure. This case represents a unique cause of pulmonary
arterial stenosis.