TITLE:
Characteristics of myosin isoforms in mammalian skeletal muscle
AUTHORS:
Priit Kaasik, Kätlin Leisson, Raivo Puhke, Karin Alev, Teet Seene
KEYWORDS:
Myosin Isoforms; Skeletal Muscle; Horses; Rats and Humans
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.2 No.2,
May
10,
2012
ABSTRACT: The distribution of myosin heavy (MyHC) and myosin light chain (MyLC) isoform pattern in horse, rat and human skeletal muscle was investigated to establish relations between them and the role of myosin isoform patterns in mammalian muscle with different twitch characteristics was studied. These two isoforms were separated in a SDS-PAGE gel system, stained using the coomassie and silver staining procedures, and the results were analyzed using a G:BOX system. The relative content of MyHC I isoform in muscle was 2.6 times higher than in human compared to horse muscle (p