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https://doi.org/10.1021/jm049806q

has been cited by the following article:

• TITLE: Synthesis, Characterization, and Antioxidation Evaluation of Novel Spiro-5-(fluoren-9’-yl)-6-azauracil and Their N,N-Dialkyl Derivatives

  AUTHORS: Hafsa Sayed, Dina A. Bakhotmah

  KEYWORDS: N, N-Disubstituted, 6-Azauracil, Fluoren-9-One, 1, 2, 4-Triazine, Antioxidant

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.10 No.4, November 27, 2020

  ABSTRACT: In search for new antioxidant agents derived from 6-azauracil, the spiro-5-(flurin-9’-yl)-6-azauracil 3 and their N,N-disubstituted-6-azauracils 4 - 17 have been synthesized using various methods and reaction conditions. Structure of the new synthesized compounds was deduced from elemental analysis and spectral measurements, for example IR, 1H/13C NMR and mass spectroscopy. The antioxidant evaluation of the new targets showed that the activity increases in the order of 8 > 10 > 6 > 7 > 9 in comparison with 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and ascorbic acid as standards.