TITLE:
Pattern of Gynaecological Malignancies in a Tertiary Care Hospital
AUTHORS:
Sayma Afroz, Gulshan Ara, Fahmida Sultana
KEYWORDS:
Gynaecological Malignancies, Histopathology, Stage, Bangladesh
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.9 No.4,
April
11,
2019
ABSTRACT: Background: Gynaecological malignancies are the second most
common cancer of females after cancer breast. Gynaecological malignancies contribute significantly to cancer burden and have a higher rate of mortality and morbidity. Carcinoma
cervix is the commonest gynaecological malignancy in developing countries while in developed countries, ovarian cancer
is the commonest. Comprehensive statistics on gynecologic malignancies reported from
Bangladesh are deficient. This study was performed to ascertain the profile of
gynecologic cancers reported at our center regarding demography, the frequency of
involvement at various sites, clinical
presentation, incidence, histologic subtypes and stage at presentation. Methods: This is a retrospective study where the records of the Departments of
Gynecology and Pathology at Enam Medical College & Hospital, Dhaka,
Bangladesh were retrospectively reviewed to identify all cases of Gynecologic
malignancies and to determine the pattern of gynaecological malignancies identified between January 2015 and December, 2018. Results: Cervical cancer (53%) was the most common gynaecological malignancy, followed by ovarian
cancer (29%), uterine cancer (8%), vulvar cancer (5%) and gestational
trophoblastic neoplasm (GTN 5%). In the case of cervical and ovarian cancer the most common age group was 41 - 50
years and gestational trophoblastic neoplasm (GTN). The majority
of patients presented at the ages of 31 - 40
years while uterine cancer presented in the elderly (>60 years). Among the
patients studied 88% were multiparous. Of the cervical cancer cases, 96.22%
was squamous cell carcinoma and commonest presenting complains were contact bleeding (33.96%)
and excessive and irregular menstruation (26.41%).
Among ovarian tumor cases 69% had
epithelial while 31% had non-epithelial
cancer and predo&