TITLE:
Hypolipidemic Activity of Olive Oil (Olea europaea) against High Fat Diet-Induced Nonalcoholic Fatty Liver Disease (NAFLD) in Mice
AUTHORS:
Farooq Ahmed Wani, Abdalla Z. Albahrawy, Shaik Rahiman
KEYWORDS:
Nonalcoholic Fatty Liver Disease, Olive Oil, High Fat Diet, Liver
JOURNAL NAME:
Open Journal of Pathology,
Vol.5 No.3,
June
16,
2015
ABSTRACT: Aim: The aim of the present study is to
access the effect of olive oil supplementation against high fat diet induced
fatty liver disease in mice. Methods: Mice were divided into five groups: Group
I (normal diet), Group II (high fat diet), Group III (olive oil), Group IV and
V (High Fat Diet along with olive oil). All mice were fed for 16 weeks with
weight measurements every 2 weeks and then sacrificed. Biochemical analysis of
blood samples was done and mice livers were histologically examined. Results: Group
II mice showed significant increase in body weight as compared with Group I (p