TITLE:
Microalbuminuria in White and Black Hypertensive Nondiabetic Brazilian Patients
AUTHORS:
Andreza Alves Belo, Eduardo Luis Guimarães Machado, Amintas Fabiano de Souza Figueiredo, Estêvão Lanna Figueiredo
KEYWORDS:
Albumin Creatinine Rate, Microalbuminuria, Primary Hypertension, Ethnic Groups, Brazilian
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.4 No.5,
May
6,
2014
ABSTRACT: Microalbuminuria (MAU) is a predictor of cardiovascular mortality in patients with diabetes mellitus (DM) and hypertension (HTN) and also in an unselected population. The American Diabetes Association (ADA) and the National Kidney Foundation (NKF) define MAU as an albumin/creatinine ratio (ACR) between 30 and 300 μg/mg in both men and women. Aim: To evaluate the possible relationship among MAU, HTN and gender and ethnicity in Brazilian nondiabetic primary hypertensive patients. Design: Population-based study. Participants: Ninety-eight men and women, seventy-two black and twenty-six white nondiabetic primary hypertensive patients aged 20 years or older were selected. Forty healthy individuals, paired according to age, gender, and ethnics were used as controls. Methods: Early-morning midstream urine was used. Urinary albumin was spectrophotometrically measured with Coomassie Brillant Blue G-250. Creatinine was determined by a method based on Jaffe’s reaction. ACR (μg albumin/mg creatinine) was calculated. Data are expressed as medians. Results: ACR level was significantly higher in 98 hypertensive patients (38.00) than in 40 control individuals (23.00) (P