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Higashiyama, M., Doi, O., Kodama, K., Yokouchi, H., Tateishi, R., Horai, T., Ashimura, J., Nagumo, S. and Naruse, Y. (1997) Pleural Lavage Cytology Immediately after Thoracotomy and before Closure of the Thoracic Cavity for Lung Cancer without Pleural Effusion and Dissemination: Clinicopathologic and Prognostic Analysis. Annals of Surgurgical Oncology, 4, 409-415.
http://dx.doi.org/10.1007/BF02305554
has been cited by the following article:
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TITLE:
Five-Year Survivors of Non-Small Cell Lung Cancer Patients with Positive Pleural Lavage Cytology
AUTHORS:
Masaki Tomita, Takanori Ayabe, Eiichi Chosa, Kunihide Nakamura
KEYWORDS:
Pleural Lavage Cytology Positive; Non-Small Cell Lung Cancer; 5-Year Survivor
JOURNAL NAME:
Advances in Lung Cancer,
Vol.3 No.1,
February
24,
2014
ABSTRACT:
Background: The pleural lavage cytology (PLC) for non-small cell lung
cancer (NSCLC) patients has been reported as a significant prognostic factor.
The aim of this study is to clarify the clinicopathological characteristics of
5-year survivors of patients with positive PLC. Methods: Among 401 resected
NSCLC patients, 30 (7.48%) patients with positive PLC were reviewed
retrospectively. Results: Only 7 of 30 patients (23.3%) survived more than
5-year. There were no differences in age, gender, histology, pT status and pN
status between 5-year survivors and non-survivors. On the other hand, the serum
carcinoembryonic antigen (CEA) level was significantly higher in non-survivors.
Among these 5-year survivors, 4 of 7 patients died of NSCLC recurrences more
than 5 years after surgery. Remaining 3 patients survived without cancer
recurrences. Interestingly these 3 survivors had not received any adjuvant
therapies after surgery. Conclusion: None of the 5-year survivor with positive
PLC had high serum CEA level. Furthermore 5-year survival did not equal to cure
in NSCLC patients with positive PLC.
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