Lau, J.Y., Sung, J., Hill, C., Henderson, C., Howden, C.W. and David, C.M. (2011) Systematic Review of the Epidemiology of Complicated Peptic Ulcer Disease: Incidence, Recurrence, Risk Factors and Mortality. Digestion, 84, 102-113.
https://pubmed.ncbi.nlm.nih.gov/21494041

has been cited by the following article:

• TITLE: The Evolutionary Profile of Patients Operated for Peptic Ulcer Perforation in Bujumbura

  AUTHORS: Jean Claude Mbonicura, Prudence Bukuru, Stanislas Harakandi, Frank Ijeneza, Révérien Ndayirorere, François Nduwimana, Astère Mbonicura

  KEYWORDS: Peritonitis, Peptic Ulcer Perforation, Complications

  JOURNAL NAME: Surgical Science, Vol.15 No.1, January 16, 2024

  ABSTRACT: Background: The evolutionary profile of patients operated for peptic ulcer perforation in Bujumbura. Perforated peptic ulcer is a serious complication of peptic ulcer with potential risk of grave complications. Aim: To study the early morbidity and mortality of surgery for peptic ulcer perforation in Bujumbura City Hall hospitals: Kamenge University Hospital Center (CHUK), Kamenge Military Hospital (HMK) and Prince Louis Rwagasore Clinic (CPLR). Patients and methods: This is a retrospective, descriptive and analytical study carried out in the three hospitals of Bujumbura over a period of three years from January 1, 2020 to December 31, 2022. It involved 57 cases (n = 57) of peptic ulcer perforation. Results: The frequency of surgery for peptic ulcer perforation was 2.7% with a mean age of 43.6 years +/-15.3 years and a male predominance with a sex ratio of 3.7. Eight percent of patients presented with shock, 24.5% were smokers, and 67.9% had taken non steroidal anti-inflammatory drugs. The mean hospital stay was 15.2 days with a standard deviation of 12.1. The morbidity rate was 30.2%, 32% were classified in grade IIIb of the Clavien-Dindo Surgical Complications Scale. There were 9 deaths (17%). Seven patients who underwent surgery and received late consultations died. Conclusion: Surgery for peptic ulcer perforation remains an intervention associated with a high rate of morbidity and mortality in Bujumbura. Surgery for peptic ulcer perforation remains a procedure associated with a high morbidity and mortality rate in Bujumbura. The time before consultation was the only factor associated with early morbidity and mortality of Surgery for peptic ulcer’s perforations.