A. J. Rodger, Z. Fox, J. D. Lundgren, L. H. Kuller, C. Boesecke, D. Gey, A. Skoutelis, M. B. Goetz, A. N. Phillips and INSIGHT Strategies for Management of Antiretroviral Therapy (SMART) Study Group, “Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection,” The Journal of Infectious Diseases, Vol. 200, No. 6, 2009, pp. 973-983. doi:10.1086/605447

has been cited by the following article:

• TITLE: Immune Activation in HIV-Infected Patients Treated with Different ARV Regimens

  AUTHORS: Alessia Uglietti, Sergio Lo Caputo, Marinella Lauriola, Michele De Gennaro, Elisabetta Chiesa, Massimo Coen, Roberta Terzi, Dorothy H. Bray, Renato Maserati, Daria Trabattoni, Mario Clerici

  KEYWORDS: HIV; Immune Activation; Antiretroviral Therapy

  JOURNAL NAME: World Journal of AIDS, Vol.2 No.2, June 15, 2012

  ABSTRACT: Objectives: To evaluate the effects of starting therapy with either Truvada (TVD) or Combivir (CBV) in combination with Efavirenz (EFV) or a boosted Protease Inhibitor (LPV/r, ATV/r, fAPV/r and SQV/r) on clinical, immunological, and virological parameters in HIV-infected antiretroviral (ARV) naive patients. Methods: Twenty-seven patients were prospectively enrolled and received TVD-EFV, 32 TVD-PI/r, 24 CBV-EFV, and 23 CBV-PI/r. Immunovirological analyses were performed at baseline and after 3, 6, 9 and 12 months after initiation of therapy; a full set of data is available for 51 patients. Results: Median CD4+ cell counts and HIV-RNA plasma viremia were comparable in the four groups of patients (TVD-EFV, TVD-PI/r, CBV-EFV, CBV-PI/r) at baseline. At month 12 HIV RNA plasma viremia was