Di Cosola, M., Cazzolla, A.P., Charitos, I.A., Ballini, A., Inchingolo, F. and Santacroce, L. (2021) Candida albicans and Oral Carcinogenesis. A Brief Review. Journal of Fungi, 7, Article No. 476.
https://doi.org/10.3390/jof7060476

has been cited by the following article:

• TITLE: Synthesis and Anticandidosic Activities of Some 3-Imidazo[1,2-a]Pyridinyl-1-Arylpropenone Derivatives

  AUTHORS: Kouassi Francesco Adingra, Souleymane Coulibaly, Kacou Alain, Mahama Ouattara, Drissa Sissouma

  KEYWORDS: Imidazo[1, 2-a]Pyridine, Arylpropenone, Candida albicans, Antifungal

  JOURNAL NAME: Advances in Biological Chemistry, Vol.12 No.4, August 11, 2022

  ABSTRACT: In this work, we show the synthesis of ten (10) new derivatives of 3-imidazo [1,2-a]pyridinyl-1-arylpropenone (10a - d). These new compounds were obtained by condensation of Claisen-Schmidt between derivatives of 2-substi- tuted-1H-imidazo[1,2-a]pyridine-3-carbaldehyde (3a - b and 7) and acetophenone derivatives (9a - e) in the presence of a base. The synthesized compounds were characterized by spectroscopic analyses 1H and 13C NMR. The antifungal activity of the ten (10) derivatives was determined on a resistant strain of Candida albicans by the microdilution method. The results showed that four (4) of them (10a, 10b, 10c and 10i) were active with minimum inhibitory concentrations (MICs) below 300 μmol/L. Of these four compounds, 10i was more potent than the others with a MIC of 41.98 μmol/L.