TITLE:
Study on the Safety of Different Pressure Artificial Pneumothorax on Endoscopic Radical Esophagectomy
AUTHORS:
Yafei Bao, Lei Zhang, Liang Zhen, Bo Jiang, Chen Yang
KEYWORDS:
Esophageal Cancer, Minimally Invasive Surgery, Single Lumen Tracheal Intubation, Artificial Pneumothorax
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.13 No.4,
April
22,
2022
ABSTRACT: Objective:
To study the effect of different pressure artificial pneumothorax on total
endoscopic radical esophagectomy during and after an operation. Methods: From 2019 to 2021,
64 patients with esophageal cancer underwent video-assisted thoracoscopic surgery in the same surgical treatment group. The pressure of CO2 artificial pneumothorax was randomly divided into Group A (pressure 6 mmHg),
Group B (pressure 8 mmHg), and Group C (pressure 10 mmHg). Heart rate (HR), mean arterial pressure
(MAP), end-expiratory CO2 partial pressure (PETCO2),
arterial blood pH and PaCO2, operation time, intraoperative blood
loss, and anesthesia resuscitation time were recorded at different time
points. Observe the changes in inflammatory indexes, coagulation function, and the
incidence of complications in the three groups, and statistically analyze and
compare the differences among the three groups of patients. Results: Sixty-four
patients with esophageal cancer were included in this clinical study. There were
no significant differences in gender, age, lung function, BMI, and
coagulation function among the three groups (P > 0.05). There were
significant differences in PETCO2, arterial pH, and PaCO2 in T2, T3, and T4 among the three groups (P , and
prothrombin time in Group A was significantly different from those in Group B and C (P , and
other complications (P > 0.05). Conclusion: The artificial pneumothorax with
6 mmHg pressure and 8 L/min flow rate can satisfy the operation, and its
safety and postoperative recovery are also better.