TITLE:
Etiologies of Bone Metastases at the Rheumatology Department (UTH) of Abidjan
AUTHORS:
Mariam Gbané, Jean Claude Soglo, Mohamed Diomandé, Guy Léopold Kengni, Baly Ouattara, Jean Mermoz Djaha Kouassi, You Nina Carmelle Kpami, Yaya Coulibaly, Edmond Eti
KEYWORDS:
Bone Metastases, Bone Condensation, Prostate Cancer, Africa
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.10 No.1,
December
6,
2019
ABSTRACT: Objectives: The aim of this study was to describe the diagnostic and etiological
aspects of bone metastases in the Rheumatology Department of Cocody’s
University Teaching Hospital (UTH). Methodology: This was a descriptive,
11-year retrospective study (January 1, 2006 to December 31, 2016) of inpatient
records of bone metastases. The diagnosis was made on clinical (bone
signs), radiological (osteolysis, bone condensation) and sometimes histological
basis. Result: Eighty out of 6, 1111 inpatients suffered from bone metastasis
with a hospital frequency of 1.30%. The average age was 60.74 years (range
26 to 81 years). Men were predominant (53 men for 27 women) with a sex ratio
of 1.96. The main complaints were pain (97.6%). chronic (90%), severe
(73.8%), inflammatory (93.8%). There was sometimes a neurological complication:
a motor deficit (21.3%), sensitive (13.8%). These symptoms were associated
with fever (56.3%) and altered general state (85%). Bone metastases
have been revealing in the vast majority of cases (93.75%); the primary cancer
was known only in 5 patients (prostate = 2, breast = 2 and cervix = 1). Bone
condensation (61.3%), osteolysis (50%) and mixed lesions (7.5%) where the
main radiological lesions observed. The primary tumors were: prostatic
(50%), pulmonary (18.8%), mammary (11.3%), uterine (5%), renal (2.5%),
hepatic (2.5%), bladder (1.3%) and adrenal (1.3%). Conclusion: Bone metastases
affect mostly the elderly; inflammatory spinal pain is the main symptom.
Bone condensation is the most common radiologic lesion. The prostate,
breast and lungs are the main primary tumors.