TITLE:
Serum Zinc, Copper and Albumin in Paired Mothers and Their Term Newborn in a Tertiary Hospital in Nigeria
AUTHORS:
Ayodele Ojuawo, Aishat Saka, Omotayo Adesiyun, Tope Obasa, Bunmi Olarinoye, Kike Adesina, Abayomi Biliaminu, Adedeji Aderibigbe, Musibau AdulAzeez
KEYWORDS:
Maternal-Newborn Pair, Zinc, Copper, Albumin
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.8 No.3,
September
21,
2018
ABSTRACT: Objective: This study assessed the serum zinc, copper and albumin levels in paired
mother and newborns in the immediate neonatal period to establish the relationship between
the pair, and the influence of maternal micronutrient status on that of the
newborn if any. Methods: The
sociodemographic characteristics of the mothers were obtained using a
structured questioner after informed consent was obtained from the parents of the baby. At
delivery, paired mother and newborns had their serum zinc, copper and albumin
assayed, using cord blood in the newborn. Result: One hundred and thirty five mothers and their paired term newborns
completed the study. The mean age of the mothers was 29.2 ± 4.6 years
with 67% within the age bracket 20 to 30 years. Seventy three percent of the
mothers attained tertiary education and 22% had secondary education. The mean serum zinc
was significantly higher in the newborn (3.67 ± 1.49
μmol/L) than in the mothers (2.20 ± 1.01 μmol/L),
p = 0.0001, with a feto-maternal ratio of 1.6
to 1. Copper was significantly higher in the mothers (4.27 ± 1.77
μmol/L), than in the newborns (2.84 ± 0.92
μmol/L) (p = 0.001), with a maternal-fetal ratio of 1.5 to 1. Mean serum
albumin was significantly lower in the newborns than in the mothers (p > 0.011). Conclusion: This study established that term newborns have higher serum zinc, a
lower serum copper and albumin levels than their maternal levels. The
distribution of these trace elements is probably protective in the newborns
against infection.