TITLE:
Ascites of Great Abundance Revealing a Nephrotic Congenital Syndrome at the University Teaching Hospital of Bouaké: About a Case
AUTHORS:
Kouadio Vincent Asse, Kouassi Christian Yao, Richard Azagoh-Kouadio, Serge Gohi Bi Irie, Kossonou Roland Yeboua, John Patrick Yenan, Koko Aude Aka-Tanoh, Christelle Avi
KEYWORDS:
Ascites, Congenital Nephrotic Syndrome, Finnish Type, Renal Transplantation, Cote d’Ivoire
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.8 No.1,
March
7,
2018
ABSTRACT: Congenital nephrotic syndrome (CNS) is defined as
the presence of proteinuria > 50 mg/kg/24h
associated with a protein concentration g/L or albuminemia
30 g/L in an infant less than 3 months old. The CNS is rare, of various
clinical forms dominated by the Finnish type caused by a mutation of the NPHS1
gene located on chromosome 19. The edematous syndrome is the most common mode
of discovery. We report a case discovered in an infant of 50 days admitted for ascites
of great abundance. The aim of this study was to describe the main
epidemiological, diagnostic, therapeutic and evolutionary aspects of this
syndrome. Improving the prognosis of this condition requires advocacy with the
political authorities of Cote d’Ivoire to provide Teaching Hospital for the resources needed to
perform kidney transplantation.